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BIO 140 Human Biology I - Questions and Solutions

The Adaptive Immune Response: T lymphocytes - Solutions

Review Questions

1. T cells that secrete cytokines that help antibody responses are called ________.

  1. Th1
  2. Th2
  3. regulatory T cells
  4. thymocytes

2. The taking in of antigen and digesting it for later presentation is called ________.

  1. antigen presentation
  2. antigen processing
  3. endocytosis
  4. exocytosis

3. Why is clonal expansion so important?

  1. to select for specific cells
  2. to secrete cytokines
  3. to kill target cells
  4. to increase the numbers of specific cells

4. The elimination of self-reactive thymocytes is called ________.

  1. positive selection.
  2. negative selection.
  3. tolerance.
  4. clonal selection.
5. Which type of T cell is most effective against viruses?
  1. Th1
  2. Th2
  3. cytotoxic T cells
  4. regulatory T cells

 

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Critical Thinking Questions

1. Describe the processing and presentation of an intracellular antigen.

Solution: The antigen is digested by the proteasome, brought into the endoplasmic reticulum by the TAP transporter system, where it binds to class I MHC molecules. These are taken to the cell surface by transport vesicles.

2. Describe clonal selection and expansion.

Solution: Antigen-specific clones are stimulated as their antigen receptor binds to antigen. They are then activated and proliferate, expanding their numbers. The result is a large number of antigen-specific lymphocytes.

 

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OpenStax, The Adaptive Immune Response: T lymphocytes and Their Functional Types. OpenStax CNX. Jun 28, 2013 http://cnx.org/contents/9e1ab8e9-3150-4c2a-b466-2c4763df2afe@4. © Jun 28, 2013 OpenStax. Textbook content produced by OpenStax is licensed under a Creative Commons Attribution License 3.0 license.